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Sir John Gurdon From Egg to Adult and Back Again Lecture I: How Does an Egg Make an Organism? Some General Principles Wednesday and Thursday, March 15 and 16, 2006 - 4:10 p.m. Pioneering cell biologist Sir John Gurdon’s ground-breaking studies in nuclear transplantation galvanized efforts to “clone” a mammal from an adult cell—a quest that in 1996 produced a healthy sheep named “Dolly.” The intellectual driving force behind this success was Gurdon’s discovery that cells of the body are capable of differentiating into all cell types of a vertebrate animal. Gurdon provided unprecedented evidence that nuclear transplantations from specialized cells could give rise to adult, fertile genetic copies of their donor. His findings also yielded wide-ranging medical implications for the use of stem cells in tissue therapy. Gurdon recently revisited this field to study nuclear reprogramming and cell fate determination in amphibians. Gurdon is an active researcher at The Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, and served as its first chairman from 1988-2001.
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